The Eukaryotic Single-Cell Genomics is a facility under SciLifeLab.
The Eukaryotic Single-Cell Genomics (ESCG) facility, aims at providing single cell transcriptomics and genomics services to the scientific community. Single cell analysis is an emerging technology that allows for the exploration of the transcriptome and genome content of individual cells. The facility offers streamlined single cell RNA sequencing, as well as whole genome DNA amplification to the scientific community, in Sweden and beyond.
Here is a list of potential applications that you could use our facility for:
- Study heterogeneity within putatively homogenous cell populations
- Unbiased discovery of cell types in complex tissues
- Characterizing the cellular and genetic composition of tumors
- Marques, S., van Bruggen, D., Vanichkina, D.P., Floriddia, E.M., Munguba, H., Väremo, L., Giacomello, S., Falcão, A.M., Meijer, M., Björklund, Å.K. and Hjerling-Leffler, J., 2018. Transcriptional Convergence of Oligodendrocyte Lineage Progenitors during Development. Developmental cell, 46(4), pp.504-517. PMID: 30078729
- Furlan, A., Dyachuk, V., Kastriti, M.E., Calvo-Enrique, L., Abdo, H., Hadjab, S., Chontorotzea, T., Akkuratova, N., Usoskin, D., Kamenev, D. and Petersen, J., 2017. Multipotent peripheral glial cells generate neuroendocrine cells of the adrenal medulla. Science, 357(6346), p.eaal3753. PMID: 28684471
- Petitpré, C., Wu, H., Sharma, A., Tokarska, A., Fontanet, P., Wang, Y., Helmbacher, F., Yackle, K., Silberberg, G., Hadjab, S. and Lallemend, F., 2018. Neuronal heterogeneity and stereotyped connectivity in the auditory afferent system. Nature communications, 9(1), p.3691. PMID: 30209249
Feel free to contact us to discuss about your project.